(1):

The one of several acids of the same element (as the phosphoric acids), which actually occurs with the greatest number of hydroxyl groups; as, orthophosphoric acid. Cf. Normal.

(2):

A combining form (also used adjectively)

(3):

Connection with, or affinity to, one variety of isomerism, characteristic of the benzene compounds; - contrasted with meta- or para-; as, the ortho position; hence, designating any substance showing such isomerism; as, an ortho compound.

(4):

A combining form signifying straight, right, upright, correct, regular; as, orthodromy, orthodiagonal, orthodox, orthographic.