Revelation 16:4

Upon the rivers and fountains of waters - This is an allusion to the first Egyptian plague, Exodus 7:20 ; and to those plagues in general there are allusions throughout this chapter. It is a sentiment of the rabbins that "whatever plagues God inflicted on the Egyptians in former times, he will inflict on the enemies of his people in all later times." See a long quotation on this subject from Rabbi Tanchum in Schoettgen.