Matthew 12:48-50

Jesus’ question did not depreciate His physical mother and brothers. His answer showed that He simply gave priority to His heavenly Father and doing His will (cf. Matthew 10:37). Spiritual relationship takes precedence over physical relationship (cf. Matthew 8:18-23). This underlines the importance of believing in Jesus and giving Him first place. Jesus’ disciples become His true family. Note that the word "whoever," referring to those who do the will of God by believing on His Son, left the possibility of salvation open to anyone (cf. Matthew 11:28-30).

These verses have strong Christological implications. They also reveal more about the spiritual family that was forming around Jesus. In spite of rising opposition, God’s purposes through Messiah were advancing (cf. Matthew 12:18; Matthew 12:20).