Isaiah 63:6

And I will tread down the people in mine anger ,.... See Gill on Isaiah 63:3 ,

and make them drunk in my fury ; or with it F19 בחמתי "excandescentia mea", Junius & Tremellius; "aestu meo", Cocceius; so Gataker. the wrath of God is signified by a cup, which he gives wicked men to drink, and which is an inebriating one to them, Psalm 75:8 , and here it signifies the cup of the wine of the fierceness of God's wrath, which shall be given to mystical Babylon, to antichrist and his followers, Revelation 14:10 ,

and I will bring down their strength to the earth ; their strong kingdoms, fortified cities, and mighty men, their wealth and riches, of which they boasted, and in which they trusted; see Isaiah 26:5 . The eighteenth chapter of the Revelation is a commentary on these words.