Acts 3:17

And now, brethren ,.... He calls them brethren, because they were so according to the flesh; and to testify his cordial love and affection for them.

I wot , or "I know",

that through ignorance ye did it ; delivered up Jesus into the hands of Pilate; denied him to be the Messiah before him; preferred a murderer to him, and put him to death.

As did also your rulers ; the members of the sanhedrim, some of them; see 1 Corinthians 2:8 for others of them knew him to be the Messiah, to be sent of God, by the miracles he did, and yet blasphemously ascribed them to Satan; and so sinning against light and knowledge, in such a malicious manner, sinned the sin against the Holy Ghost, to which ignorance is here opposed; and which did not excuse from sin: nor was it itself without sin; nor is it opposed to any sin, but to this now mentioned.