Verse 16
16. Shed innocent blood Probably of those prophets (comp. 2 Kings 21:10) who reproved his sins and uttered the word of the Lord against him. Josephus says, “He barbarously slew all the righteous men that were among the Hebrews; nor would he spare the prophets, for he every day slew some of them, till Jerusalem was overflown with blood.” It was during the reign of Manasseh, according to Jewish tradition, that Isaiah was sawn asunder. Hebrews 11:37.
Besides his sin That is, especially, his abominable idolatry.
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