(1):

(n.) The root of Spigelia Marilandica, used as a powerful vermifuge; also, that of S. Anthelmia. See definition 2 (below).

(2):

(n.) A perennial North American herb (Spigelia Marilandica), sometimes cultivated for its showy red blossoms. Called also Carolina pink, Maryland pinkroot, and worm grass.

(3):

(n.) An annual South American and West Indian plant (Spigelia Anthelmia).