(1):

(n.) An unpropitious or baleful aspect of a planet or star; malevolent influence of a heavenly body; hence, an ill portent.

(2):

(n.) An adverse or unfortunate event, esp. a sudden and extraordinary misfortune; a calamity; a serious mishap.

(3):

(v. t.) To blast by the influence of a baleful star.

(4):

(v. t.) To bring harm upon; to injure.