(1):

(superl.) Inclining to shrew; disposing to curse or scold; hence, vicious; malicious; evil; wicked; mischievous; vexatious; rough; unfair; shrewish.

(2):

(superl.) Artful; wily; cunning; arch.

(3):

(superl.) Able or clever in practical affairs; sharp in business; astute; sharp-witted; sagacious; keen; as, a shrewd observer; a shrewd design; a shrewd reply.