Mateo 10:11

And into whatsoever city or village ye shall enter, search out who in it is worthy; and there abide till ye go forth.

Among the Israelites, there were many, perhaps, in that day, like aged Simeon, who were looking for "the consolation of Israel"; and it was into such homes that the apostles were to go. The prohibition on going from house to house was strongly in their best interests and would prevent their being caught up in a round of dinners, entertainment, and social activities, which, although innocent in themselves, would have seriously hampered their work. In our own times, many a gospel meeting has been hindered by the constant shuttling of the messenger from place to place, three or four times a day, to eat here, to eat there, or to visit yonder, and to be entertained.