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Want to know what the Bible says about Despair? Here are 108 Bible verses about Despair from the Old and New Testaments of the Holy Bible, New International Version (NIV), sorted from the most relevant to the least relevant.

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Note: Always check the context of a verse; Click the "Read Full Chapter" button next to each verse to read more. The context of a verse might put a very different slant on what the verse seems to say.

Exodus 6:9 NIV
Moses reported this to the Israelites, but they did not listen to him because of their discouragement and harsh labor.
16
Psalm 32:10 NIV
Many are the woes of the wicked,
    but the Lord’s unfailing love
    surrounds the one who trusts in him.
16
Isaiah 46:4 NIV
Even to your old age and gray hairs
    I am he, I am he who will sustain you.
I have made you and I will carry you;
    I will sustain you and I will rescue you.
16
Hebrews 12:2-3 NIV
2 fixing our eyes on Jesus, the pioneer and perfecter of faith. For the joy set before him he endured the cross, scorning its shame, and sat down at the right hand of the throne of God. 3 Consider him who endured such opposition from sinners, so that you will not grow weary and lose heart.
16
Romans 8:38-39 NIV
38 For I am convinced that neither death nor life, neither angels nor demons, neither the present nor the future, nor any powers, 39 neither height nor depth, nor anything else in all creation, will be able to separate us from the love of God that is in Christ Jesus our Lord.
15
2 Corinthians 4:7 NIV
But we have this treasure in jars of clay to show that this all-surpassing power is from God and not from us.
15
2 Corinthians 1:3-4 NIV
3 Praise be to the God and Father of our Lord Jesus Christ, the Father of compassion and the God of all comfort, 4 who comforts us in all our troubles, so that we can comfort those in any trouble with the comfort we ourselves receive from God.
14
Isaiah 9:1 NIV
Nevertheless, there will be no more gloom for those who were in distress. In the past he humbled the land of Zebulun and the land of Naphtali, but in the future he will honor Galilee of the nations, by the Way of the Sea, beyond the Jordan—
13
1 Peter 4:12-13 NIV
12 Dear friends, do not be surprised at the fiery ordeal that has come on you to test you, as though something strange were happening to you. 13 But rejoice inasmuch as you participate in the sufferings of Christ, so that you may be overjoyed when his glory is revealed.
13
Isaiah 40:31 NIV
but those who hope in the Lord
    will renew their strength.
They will soar on wings like eagles;
    they will run and not grow weary,
    they will walk and not be faint.
13

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