“That view of the Cross, it cannot be denied, runs counter to the mind of the natural man. It is not, indeed, complicated or obscure; on the contrary it is so simple that a child can understand, and what is really obscure is the manifold modern effort to explain the Cross away in such fashion as to make it more agreeable to human pride.”
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Born in Baltimore, Maryland, he came from a wealthy and well-educated background. He studied at John Hopkins University and then went to Princeton Theological Seminary, receiving an M.A. in philosophy. He studied in Germany and returned to teach New Testament at Princeton. He received his B.D. in 1905 and was ordained in the Presbyterian Church.
In 1929, he left Princeton Seminary when the institution capitulated to the liberal faction, and he, along with others, founded Westminster Theological Seminary. In 1934 he was censured by the Presbyterian Church for his actions in relation to the Presbyterian Board of Foreign Missions, the liberal bias of which he opposed. In 1935 he was defrocked by the Presbyterian Church over major doctrinal issues. Machen then established the Orthodox Presbyterian Church as a reaction to the liberalism of the Presbyterian hierarchy. He died at age 55, of pneumonia.