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Want to know what the Bible says about Despair? Here are 108 Bible verses about Despair from the Old and New Testaments of the Holy Bible, New International Version (NIV), sorted from the most relevant to the least relevant.

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Note: Always check the context of a verse; Click the "Read Full Chapter" button next to each verse to read more. The context of a verse might put a very different slant on what the verse seems to say.

Jeremiah 18:12 NIV
But they will reply, ‘It’s no use. We will continue with our own plans; we will all follow the stubbornness of our evil hearts. ’”
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Isaiah 8:21 NIV
Distressed and hungry, they will roam through the land; when they are famished, they will become enraged and, looking upward, will curse their king and their God.
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Revelation 16:10-11 NIV
10 The fifth angel poured out his bowl on the throne of the beast, and its kingdom was plunged into darkness. People gnawed their tongues in agony 11 and cursed the God of heaven because of their pains and their sores, but they refused to repent of what they had done.
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Revelation 6:16 NIV
They called to the mountains and the rocks, “Fall on us and hide us from the face of him who sits on the throne and from the wrath of the Lamb!
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Lamentations 3:18 NIV
So I say, “My splendor is gone
    and all that I had hoped from the Lord.”
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Genesis 4:13-14 NIV
13 Cain said to the Lord, “My punishment is more than I can bear. 14 Today you are driving me from the land, and I will be hidden from your presence; I will be a restless wanderer on the earth, and whoever finds me will kill me.”
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2 Samuel 17:23 NIV
When Ahithophel saw that his advice had not been followed, he saddled his donkey and set out for his house in his hometown. He put his house in order and then hanged himself. So he died and was buried in his father’s tomb.
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Matthew 27:5 NIV
So Judas threw the money into the temple and left. Then he went away and hanged himself.
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