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Want to know what the Bible says about Despondency? Here are 36 Bible verses about Despondency from the Old and New Testaments of the Holy Bible, New International Version (NIV), sorted from the most relevant to the least relevant.

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Note: Always check the context of a verse; Click the "Read Full Chapter" button next to each verse to read more. The context of a verse might put a very different slant on what the verse seems to say.

Numbers 17:12-13 NIV
12 The Israelites said to Moses, “We will die! We are lost, we are all lost! 13 Anyone who even comes near the tabernacle of the Lord will die. Are we all going to die?”
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Deuteronomy 28:65-67 NIV
65 Among those nations you will find no repose, no resting place for the sole of your foot. There the Lord will give you an anxious mind, eyes weary with longing, and a despairing heart. 66 You will live in constant suspense, filled with dread both night and day, never sure of your life. 67 In the morning you will say, “If only it were evening!” and in the evening, “If only it were morning!”—because of the terror that will fill your hearts and the sights that your eyes will see.
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Job 17:13-16 NIV
13 If the only home I hope for is the grave,
    if I spread out my bed in the realm of darkness,
14 if I say to corruption, ‘You are my father,’
    and to the worm, ‘My mother’ or ‘My sister,’
15 where then is my hope—
    who can see any hope for me?
16 Will it go down to the gates of death?
    Will we descend together into the dust?”
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Psalm 31:22 NIV
In my alarm I said,
    “I am cut off from your sight!”
Yet you heard my cry for mercy
    when I called to you for help.
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Psalm 77:7-9 NIV
7 “Will the Lord reject forever?
    Will he never show his favor again?
8 Has his unfailing love vanished forever?
    Has his promise failed for all time?
9 Has God forgotten to be merciful?
    Has he in anger withheld his compassion?
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Proverbs 13:12 NIV
Hope deferred makes the heart sick,
    but a longing fulfilled is a tree of life.
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Isaiah 2:19 NIV
People will flee to caves in the rocks
    and to holes in the ground
from the fearful presence of the Lord
    and the splendor of his majesty,
    when he rises to shake the earth.
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Jeremiah 2:25 NIV
Do not run until your feet are bare
    and your throat is dry.
But you said, ‘It’s no use!
    I love foreign gods,
    and I must go after them.’
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Jeremiah 8:20 NIV
“The harvest is past,
    the summer has ended,
    and we are not saved.”
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Jeremiah 18:12 NIV
But they will reply, ‘It’s no use. We will continue with our own plans; we will all follow the stubbornness of our evil hearts. ’”
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